Structure of PDB 2awn Chain C

Receptor sequence
>2awnC (length=344) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
ASVQLQNVTVSKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLGVGMVF
QSYALYPHLSVAENMSFGLKLAGAKKEVINQRVNQVAEVLQLAHLLDRKP
KALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLDAALRVQMRIEISRLHK
RLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPADRFVA
GFIGSPKMNFLPVKVTATAIDQVQVELPMPNRQQVWLPVESRDVQVGANM
SLGIRPEHLLPSDIADVILEGEVQVVEQLGNETQIHIQIPSIRQNLVYRQ
NDVVLVEEGATFAIGLPPERCHLFREDGTACRRLHKEPGVASAS
3D structure
PDB2awn ATP hydrolysis is required to reset the ATP-binding cassette dimer into the resting-state conformation.
ChainC
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.5.2.1: ABC-type maltose transporter.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP C V18 G39 C40 G41 K42 S43 T44 V10 G31 C32 G33 K34 S35 T36
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0015423 ABC-type maltose transporter activity
GO:0016887 ATP hydrolysis activity
GO:0022857 transmembrane transporter activity
GO:0140297 DNA-binding transcription factor binding
GO:0140359 ABC-type transporter activity
Biological Process
GO:0008643 carbohydrate transport
GO:0015768 maltose transport
GO:0034763 negative regulation of transmembrane transport
GO:0042956 maltodextrin transmembrane transport
GO:0055085 transmembrane transport
GO:1902344 negative regulation of maltose transport
GO:1904981 maltose transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0032991 protein-containing complex
GO:0043190 ATP-binding cassette (ABC) transporter complex
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
GO:1990060 maltose transport complex
GO:1990154 enzyme IIA-maltose transporter complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2awn, PDBe:2awn, PDBj:2awn
PDBsum2awn
PubMed16326809
UniProtP68187|MALK_ECOLI Maltose/maltodextrin import ATP-binding protein MalK (Gene Name=malK)

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