Structure of PDB 2aob Chain C

Receptor sequence
>2aobC (length=96) Species: 9606 (Homo sapiens) [Search protein sequence]
KPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDV
QHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDI
3D structure
PDB2aob Crystal Structures of a High-affinity Macrocyclic Peptide Mimetic in Complex with the Grb2 SH2 Domain.
ChainC
Resolution1.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 S1S C R67 R86 S88 E89 S90 S96 H107 F108 K109 L111 L120 R12 R31 S33 E34 S35 S41 H52 F53 K54 L56 L65
BS02 S1S C D113 A115 K117 R142 D58 A60 K62 R87
BS03 S1S C E87 G93 F95 Y118 E32 G38 F40 Y63
BS04 S1S C H58 W60 F61 H3 W5 F6
External links
PDB RCSB:2aob, PDBe:2aob, PDBj:2aob
PDBsum2aob
PubMed16165154
UniProtP62993|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)

[Back to BioLiP]