Structure of PDB 2amf Chain C

Receptor sequence
>2amfC (length=256) Species: 160490 (Streptococcus pyogenes M1 GAS) [Search protein sequence]
MKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLALPYAMS
HQDLIDQVDLVILGIKPQLFETVLKPLHFKQPIISMAAGISLQRLATFVG
QDLPLLRIMPNMNAQILQSSTALTGNALVSQELQARVRDLTDSFGSTFDI
SEKDFDTFTALAGSSPAYIYLFIEALAKAGVKNGIPKAKALEIVTQTVLA
SASNLKTSSQSPHDFIDAICSPGGTTIAGLMELERLGLTATVSSAIDKTI
DKAKSL
3D structure
PDB2amf Crystal Structures of Delta(1)-Pyrroline-5-carboxylate Reductase from Human Pathogens Neisseria meningitides and Streptococcus pyogenes
ChainC
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.5.1.2: pyrroline-5-carboxylate reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PRO C M11 P110 M11 P110
BS02 PRO C S221 G224 T225 T226 S221 G224 T225 T226
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004735 pyrroline-5-carboxylate reductase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006561 proline biosynthetic process
GO:0055129 L-proline biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2amf, PDBe:2amf, PDBj:2amf
PDBsum2amf
PubMed16233902
UniProtQ9A1S9

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