Structure of PDB 1zc4 Chain C

Receptor sequence
>1zc4C (length=173) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGE
EVQIDILDTAGLEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQ
ILRVKEDENVPFLLVGNKSDLEDKRQVSVEEAKNRAEQWNVNYVETSAKT
RANVDKVFFDLMREIRARKMEDS
3D structure
PDB1zc4 Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase.
ChainC
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG C S28 T46 S18 T36
BS02 GNP C G24 G26 K27 S28 A29 F39 E41 Y43 T46 G71 K128 D130 S157 K159 G14 G16 K17 S18 A19 F29 E31 Y33 T36 G61 K118 D120 S147 K149
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:1zc4, PDBe:1zc4, PDBj:1zc4
PDBsum1zc4
PubMed15920473
UniProtP11233|RALA_HUMAN Ras-related protein Ral-A (Gene Name=RALA)

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