Structure of PDB 1z69 Chain C

Receptor sequence
>1z69C (length=327) Species: 2208 (Methanosarcina barkeri) [Search protein sequence]
MKFGIEFVPSDPALKIAYYAKLSEQQGFDHVWITDHYNNRDVYSTLTVLA
LNTNSIKIGPGVTNSYTRNPAITASSIASIAEISGGRAVLGLGPGDKATF
DAMGIAWKKPLATTKEAIQAIRDFISGKKVSMDGEMIKFAGAKLAFKAGN
IPIYMGAQGPKMLELAGEIADGVLINASHPKDFEVAVEQIKKGAEKAGRD
PSEVDVTAYACFSIDKDPVKAVNAAKVVVAFIVAGSPDLVLERHGIPVEA
KSQIGAAIAKGDFGALMGGLVTPQMIEAFSICGTPDDCMKRIKDLEAIGV
TQIVAGSPIGPAKEKAIKLIGKEIIAK
3D structure
PDB1z69 Crystal structure of methylenetetrahydromethanopterin reductase (Mer) in complex with coenzyme F420: Architecture of the F420/FMN binding site of enzymes within the nonprolyl cis-peptide containing bacterial luciferase family
ChainC
Resolution2.61 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H36 Y37 D96
Catalytic site (residue number reindexed from 1) H36 Y37 D96
Enzyme Commision number 1.5.98.2: 5,10-methylenetetrahydromethanopterin reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 F42 C T34 D35 H36 G61 V62 P94 G95 D96 K109 P110 L111 A157 Q158 G159 P160 K161 M162 L174 N176 Y209 T34 D35 H36 G61 V62 P94 G95 D96 K109 P110 L111 A157 Q158 G159 P160 K161 M162 L174 N176 Y209
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0018537 coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity
Biological Process
GO:0006730 one-carbon metabolic process
GO:0015948 methanogenesis
GO:0019386 methanogenesis, from carbon dioxide
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:1z69, PDBe:1z69, PDBj:1z69
PDBsum1z69
PubMed15937276
UniProtQ46FV4|MER_METBF 5,10-methylenetetrahydromethanopterin reductase (Gene Name=mer)

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