Structure of PDB 1wyu Chain C

Receptor sequence
>1wyuC (length=437) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MDYTPHTEEEIREMLRRVGAASLEDLFAHLPKEILSPPIDLPEPLPEWKV
LEELRRLAAQNLPAHKAFLGGGVRSHHVPPVVQALAARGEFLTAYTPYQP
EVSQGVLQATFEYQTMIAELAGLEIANASMYDGATALAEGVLLALRETGR
MGVLVSQGVHPEYRAVLRAYLEAVGAKLLTLPLEGGRTPLPEVGEEVGAV
VVQNPNFLGALEDLGPFAEAAHGAGALFVAVADPLSLGVLKPPGAYGADI
AVGDGQSLGLPMGFGGPHFGFLATKKAFVRQLPGRLVSETVDVEGRRGFI
LTLQAREQYIRRAKAKSNITTNAQLTALMGAMYLAALGPEGLREVALKSV
EMAHKLHALLLEVPGVRPFTPKPFFNEFALALPKDPEAVRRALAERGFHG
ATPVPREYGENLALFAATELHEEEDLLALREALKEVL
3D structure
PDB1wyu Structure of P-protein of the glycine cleavage system: implications for nonketotic hyperglycinemia
ChainC
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.4.4.2: glycine dehydrogenase (aminomethyl-transferring).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP C T320 T321 T320 T321
Gene Ontology
Molecular Function
GO:0004375 glycine dehydrogenase (decarboxylating) activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006546 glycine catabolic process
GO:0009116 nucleoside metabolic process
GO:0019464 glycine decarboxylation via glycine cleavage system

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Molecular Function
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Biological Process
External links
PDB RCSB:1wyu, PDBe:1wyu, PDBj:1wyu
PDBsum1wyu
PubMed15791207
UniProtQ5SKW8

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