Structure of PDB 1u74 Chain C

Receptor sequence
>1u74C (length=295) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
ITTPLVHVASVEKGRSYEDFQKVYNAIALKLREDDEYDNYIGYGPVLVRL
AWHISGTWDKHDNTGGSYGGTYRFKKEFNDPSNAGLQNGFKFLEPIHKEF
PWISSGDLFSLGGVTAVQEMQGPKIPWRCGRVDTPEDTTPDNGRLPDADK
DAGYVRTFFQRLNMNDREVVALMGAHALGKTHLKNSGYEGPWGAANNVFT
NEFYLNLLNEDWKLEKNDANNEQWDSKSGYMMLPTDYSLIQDPKYLSIVK
EYANDQDKFFKDFSKAFEKLLENGITFPKDAPSPFIFKTLEEQGL
3D structure
PDB1u74 Electron transfer between cytochrome c and cytochome c peroxidase in single crystals.
ChainC
Resolution2.4 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R48 H52 H175 W191 D235
Catalytic site (residue number reindexed from 1) R49 H53 H176 W192 D236
Enzyme Commision number 1.11.1.5: cytochrome-c peroxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZNH C P44 R48 W51 P145 D146 L171 M172 A174 H175 K179 T180 H181 N184 S185 W191 L232 F266 P45 R49 W52 P146 D147 L172 M173 A175 H176 K180 T181 H182 N185 S186 W192 L233 F267
Gene Ontology
Molecular Function
GO:0004601 peroxidase activity
GO:0020037 heme binding
Biological Process
GO:0006979 response to oxidative stress
GO:0034599 cellular response to oxidative stress

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Molecular Function
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Biological Process
External links
PDB RCSB:1u74, PDBe:1u74, PDBj:1u74
PDBsum1u74
PubMed15339156
UniProtP00431|CCPR_YEAST Cytochrome c peroxidase, mitochondrial (Gene Name=CCP1)

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