Structure of PDB 1sl0 Chain C

Receptor sequence
>1sl0C (length=657) Species: 10760 (Escherichia phage T7) [Search protein sequence]
MIVSDIEANALLESVTKFHCGVIYDYSTAEYVSYRPSDFGAYLDALEAEV
ARGGLIVFHNGHKYDVPALTKLAKLQLNREFHLPRENCIDTLVLSRLIHS
NLKDTDMGLLRSGKLPGALEAWGYRLGEMKGEYKDDFKRMLEEQGEEYVD
GMEWWNFNEEMMDYNVQDVVVTKALLEKLLSDKHYFPPEIDFTDVGYTTF
WSESLEAVDIEHRAAWLLAKQERNGFPFDTKAIEELYVELAARRSELLRK
LTETFGSWYQPKGGTEMFCHPRTGKPLPKYPRIKTPVGDTREYVAAPYTP
VEHVVFNPSSRDHIQKKLQEAGWVPTKYTDKGAPVVDDEVLEGVRVDDPE
KQAAIDLIKEYLMIQKRIGQSAEGDKAWLRYVAEDGKIHGSVNPNGAVTG
RATHAFPNLAQIPGVRSPYGEQCRAAFGAEHHLDGITGKPWVQAGIDASG
LELRCLAHFMARFDNGEYAHEILNGDIHTKNQIAAELPTRDNKTFIYGFK
IGQIVGAGKERGKELKKKFLENTPAIAALRESIQQTLVEKWKRRWIKGLD
GRKVHVRSPHAALNTLLQSAGALICKLWIIKTEEMLVEKGLKHGWDGDFA
YMAWVHDEIQVGCRTEEIAQVVIETAQEAMRWVGDHWNFRCLLDTEGKMG
PNWAICH
3D structure
PDB1sl0 Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7.
ChainC
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
3.1.11.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C K359 V363 V364 D365 K394 R429 A438 Q439 I440 P441 G442 S445 H653 D654 K331 V335 V336 D337 K366 R401 A410 Q411 I412 P413 G414 S417 H606 D607
BS02 dna C S337 S338 D403 K404 A425 T431 H432 F434 N436 Q439 S309 S310 D375 K376 A397 T403 H404 F406 N408 Q411
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0004527 exonuclease activity
GO:0004529 DNA exonuclease activity
GO:0005515 protein binding
GO:0008408 3'-5' exonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006302 double-strand break repair
GO:0039693 viral DNA genome replication
GO:0090592 DNA synthesis involved in DNA replication

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Molecular Function
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Biological Process
External links
PDB RCSB:1sl0, PDBe:1sl0, PDBj:1sl0
PDBsum1sl0
PubMed15235589
UniProtP00581|DPOL_BPT7 DNA-directed DNA polymerase (Gene Name=5)

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