Structure of PDB 1re3 Chain C

Receptor sequence
>1re3C (length=288) Species: 9606 (Homo sapiens) [Search protein sequence]
SIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQD
IANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFK
KNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNG
RTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFT
SHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYS
KASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLT
3D structure
PDB1re3 BbetaGlu397 and BbetaAsp398 but not BbetaAsp432 are required for "B:b" interactions.
ChainC
Resolution2.45 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C D298 D301 T305 F322 Q329 K338 C339 H340 Y363 D364 D193 D196 T200 F217 Q224 K233 C234 H235 Y258 D259
BS02 CA C D318 D320 F322 G324 D213 D215 F217 G219
BS03 CA C D294 G296 D297 D298 P299 D301 D189 G191 D192 D193 P194 D196
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1re3, PDBe:1re3, PDBj:1re3
PDBsum1re3
PubMed14992584
UniProtP02679|FIBG_HUMAN Fibrinogen gamma chain (Gene Name=FGG)

[Back to BioLiP]