Structure of PDB 1r0l Chain C

Receptor sequence
>1r0lC (length=378) Species: 542 (Zymomonas mobilis) [Search protein sequence]
MSQPRTVTVLGATGSIGHSTLDLIERNLDRYQVIALTANRNVKDLADAAK
RTNAKRAVIADPSLYNDLKEALAGSSVEAAAGADALVEAAMMGADWTMAA
IIGCAGLKATLAAIRKGKTVALANKESLVSAGGLMIDAVREHGTTLLPVD
SEHNAIFQCFPHHNRDYVRRIIITASGGPFRTTSLAEMATVTPERAVAKI
SIDSATMMNKGLELIEAFHLFQIPLEKFEILVHPQSVIHSMVEYLDGSIL
AQIGSPDMRTPIGHTLAWPKRMETPAESLDFTKLRQMDFEAPDYERFPAL
TLAMESIKSGGARPAVMNAANEIAVAAFLDKKIGFLDIAKIVEKTLDHYT
PATPSSLEDVFAIDNEARIQAAALMESL
3D structure
PDB1r0l Crystal structure of 1-deoxy-d-xylulose-5-phosphate reductoisomerase from Zymomonas mobilis at 1.9-A resolution.
ChainC
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.267: 1-deoxy-D-xylulose-5-phosphate reductoisomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NDP C G11 T13 N39 N41 I101 A105 G11 T13 N39 N41 I101 A105
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0030145 manganese ion binding
GO:0030604 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GO:0046872 metal ion binding
GO:0070402 NADPH binding
Biological Process
GO:0008299 isoprenoid biosynthetic process
GO:0019288 isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
GO:0051484 isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1r0l, PDBe:1r0l, PDBj:1r0l
PDBsum1r0l
PubMed15063313
UniProtQ9X5F2|DXR_ZYMMO 1-deoxy-D-xylulose 5-phosphate reductoisomerase (Gene Name=dxr)

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