Structure of PDB 1qvr Chain C

Receptor sequence

>1qvrC (length=803) Species: 274 (Thermus thermophilus)

ERWTQAAREALAQAQVLAQRMKHQAIDLPHLWAVLLKDERSLAWRLLEKA
GADPKALKELQERELARLPKVEGAEVGQYLTSRLSGALNRAEGLMEELKD
RYVAVDTLVLALAEATPGLPGLEALKGALKELRGGRTVQTEHAESTYNAL
EQYGIDLTRLAAEGKLDPVIGRDEEIRRVIQILLRRTKNNPVLIGEPGVG
KTAIVEGLAQRIVKGDVPEGLKGKRIVSLQMEFEERLKAVIQEVVQSQGE
VILFIDELKPALARGELRLIGATTLDEYREIEKDPALERRFQPVYVDEPT
VEETISILRGLKEKYEVHHGVRISDSAIIAAATLSHRYITERRLPDKAID
LIDEAAARLRMALESAPEEIDALERKKLQLEIEREALKKEKDPDSQERLK
AIEAEIAKLTEEIAKLRAEWEREREILRKLREAQHRLDEVRREIELAERQ
YDLNRAAELRYGELPKLEAEVEALSEKLRGARFVRLEVTEEDIAEIVSRW
TGIPVSKLLEGEREKLLRLEEELHKRVVGQDEAIRAVADAIRRARAGLKD
PNRPIGSFLFLGPTGVGKTELAKTLAATLFDTEEAMIRIDMTEYMEKHAV
SRLQLTEAVRRRPYSVILFDEIEKAHPDVFNILLQILDDGRLTDSHGRTV
DFRNTVIILTSNLGSPLILEGLQKGWPYERIRDEVFKVLQQHFRPEFLNR
LDEIVVFRPLTKEQIRQIVEIQLSYLRARLAEKRISLELTEAAKDFLAER
GYDPVFGARPLRRVIQRELETPLAQKILAGEVKEGDRVQVDVGPAGLVFA
VPA

3D structure

• PDB: 1qvr The Structure of ClpB: A Molecular Chaperone that Rescues Proteins from an Aggregated State
• Chain: C
• Resolution: 3.0 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ANP	C	P318 R322	P285 R289
BS02	ANP	C	G201 V202 G203 K204 T205 A206 I340 I382	G198 V199 G200 K201 T202 A203 I307 I349
BS03	ANP	C	V560 V561 T597 G598 V599 G600 T602 E603 I765 R806	V527 V528 T564 G565 V566 G567 T569 E570 I718 R759

Gene Ontology

Molecular Function

• GO:0005515 protein binding
• GO:0005524 ATP binding
• GO:0016887 ATP hydrolysis activity
• GO:0042802 identical protein binding

Biological Process

• GO:0009408 response to heat
• GO:0034605 cellular response to heat
• GO:0042026 protein refolding

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:1qvr, PDBe:1qvr, PDBj:1qvr
• PDBsum: 1qvr
• PubMed: 14567920
• UniProt: Q9RA63|CLPB_THET8 Chaperone protein ClpB (Gene Name=clpB)