Structure of PDB 1q5c Chain C

Receptor sequence

>1q5cC (length=540) Species: 10090 (Mus musculus)

DWVIPPIKVSENERGPFPKRLVQIKSNKDRFNKVYYSITGQGADNPPQGV
FRIEWETGWMLVTRPLDREEYDKYVLSSHAVSENGSPVEEPMEITINVID
QNDNRPKFTQDVFRGSVREGVQPGTQVMAVSATDEDDNIDSLNGVLSYSI
LKQDPEEPIPNLFTINRETGVISLIGTGLDREKFPEYTLTVQATDLEGAG
LSVEGKAIIQITDANDNAPIFDPKTYTALVPENEIGFEVQRLSVTDLDMP
GTPAWQAVYKIRVNEGGFFNITTDPESNQGILTTAKGLDFELRKQYVLQI
TVENAEPFSVPLPTSTATVTVTVEDVNEAPFFVPAVSRVDVSEDLSRGEK
IISLVAQDPDKQQIQKLSYFIGNDPARWLTVNKDNGIVTGNGNLDRESEY
VKNNTYTVIMLVTDDGVSVGTGTGTLILHVLDVNDNGPVPSPRVFTMCDQ
NPEPQVLTISDADIPPNTYPYKVSLSHGSDLTWKAELDSKGTSMLLSPTQ
QLKKGDYSIYVLLSDAQNNPQLTVVNATVCSCEGKAIKCQ

3D structure

• PDB: 1q5c Untangling Desmosomal Knots with Electron Tomography
• Chain: C
• Resolution: 30.0 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CA	C	N102 N104 D134 D136 N143 D195	N102 N104 D134 D136 N143 D195
BS02	CA	C	E11 R68 E69 D100 Q101 D103 D136	E11 R68 E69 D100 Q101 D103 D136
BS03	CA	C	E11 N12 D67 E69 D103	E11 N12 D67 E69 D103
BS04	CA	C	E119 E182 D213 A214 D216 D248	E119 E182 D213 A214 D216 D248
BS05	CA	C	E119 D180 E182 D216	E119 D180 E182 D216
BS06	CA	C	N215 N217 D246 D248 A254 N304	N215 N217 D246 D248 A254 N304
BS07	CA	C	E232 D289 F290 E291 E328	E232 D289 F290 E291 E328
BS08	CA	C	N327 E328 D358 D360 Q365 D414	N327 E328 D358 D360 Q365 D414
BS09	CA	C	E343 D395 E397 D435	E343 D395 E397 D435
BS10	CA	C	N434 N436 D461 D463 N467 D515	N434 N436 D461 D463 N467 D515
BS11	CA	C	E232 E291 D325 V326 E328 D360	E232 E291 D325 V326 E328 D360
BS12	CA	C	E343 E397 D432 V433 D435	E343 E397 D432 V433 D435

Gene Ontology

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UnboundLocalError

Python 3.6.8: /usr/bin/python3 Mon May 5 08:47:36 2025

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1471                 pubmed=display_regular_ligand(pdbid,asym_id,lig3,ligIdx,title)

   1472         else:

=> 1473             pubmed,uniprot=display_protein_receptor(pdbid,asym_id,title)

   1474     

   1475     uniprot_line=''

pubmed = '', uniprot = '', display_protein_receptor = <function display_protein_receptor>, pdbid = '1q5c', asym_id = 'C', title = 'Untangling Desmosomal Knots with Electron Tomography'

 /var/www/html/BioLiP/pdb.cgi in display_protein_receptor(pdbid='1q5c', asym_id='C', title='Untangling Desmosomal Knots with Electron Tomography')

    840 

    841     if go:

=>  842         display_go(go,uniprot,pdbid,asym_id)

    843     return pubmed,uniprot

    844 

global display_go = <function display_go>, go = '0005509,0005886,0007155,0007156,0016020,0098609', uniprot = '', pdbid = '1q5c', asym_id = 'C'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0005509,0005886,0007155,0007156,0016020,0098609', uniprot='', pdbid='1q5c', asym_id='C')

    481         '''.replace("$namespace_link",namespace_link

    482           ).replace("$namespace",namespace

=>  483           ).replace("$uniprot",u

    484         ))

    485         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>