Structure of PDB 1py1 Chain C

Receptor sequence
>1py1C (length=138) Species: 9606 (Homo sapiens) [Search protein sequence]
ETLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQS
PQEWEAIQALTVLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRT
SEKVKNKILELLYSWTVGLPEEVKIAEAYQMLKKQGIV
3D structure
PDB1py1 Biochemical and structural characterization of the interaction of memapsin 2 (beta-secretase) cytosolic domain with the VHS domain of GGA proteins.
ChainC
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C K87 F88 R89 N92 I95 Y102 K131 M138 Q142 K80 F81 R82 N85 I88 Y95 K124 M131 Q135
Gene Ontology
Molecular Function
GO:0031267 small GTPase binding
GO:0035091 phosphatidylinositol binding
GO:0043130 ubiquitin binding
Biological Process
GO:0006886 intracellular protein transport
Cellular Component
GO:0005802 trans-Golgi network

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1py1, PDBe:1py1, PDBj:1py1
PDBsum1py1
PubMed14567678
UniProtQ9UJY5|GGA1_HUMAN ADP-ribosylation factor-binding protein GGA1 (Gene Name=GGA1)

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