Structure of PDB 1pfx Chain C

Receptor sequence
>1pfxC (length=235) Species: 9823 (Sus scrofa) [Search protein sequence]
IVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCIEPGVKIT
VVAGEYNTEETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLT
LNSYVTPICIADKEYTNIFLKFGSGYVSGWGRVFNRGRSATILQYLKVPL
VDRATCLRSTKFTIYSNMFCAGFHEGGKDSCQGDSGGPHVTEVEGTSFLT
GIISWGEECAVKGKYGIYTKVSRYVNWIKEKTKLT
3D structure
PDB1pfx X-ray structure of clotting factor IXa: active site and module structure related to Xase activity and hemophilia B.
ChainC
Resolution3.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H57
Catalytic site (residue number reindexed from 1) H41
Enzyme Commision number 3.4.21.22: coagulation factor IXa.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 0G6 C H57 Y99 F174 S190 C191 Q192 S195 S214 W215 G216 H41 Y86 F162 S180 C181 Q182 S185 S204 W205 G206
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1pfx, PDBe:1pfx, PDBj:1pfx
PDBsum1pfx
PubMed7568220
UniProtP16293|FA9_PIG Coagulation factor IX (Fragment) (Gene Name=F9)

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