Structure of PDB 1oy0 Chain C

Receptor sequence
>1oy0C (length=248) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
RTKIRTHHLQRWKADGHKWAMLTAYDYSTARIFDEAGIPVLLVGDSAANV
VYGYDTTVPISIDELIPLVRGVVRGAPHALVVADLPFGSYEAGPTAALAA
ATRFLKDGGAHAVKLEGGERVAEQIACLTAAGIPVMAHIGFTPGDAAEQT
IADAIAVAEAGAFAVVMEMVPAELATQITGKLTIPTVGIGAGPNCDGQVL
VWQDMAGFSGAKTARFVKRYADVGGELRRAAMQYAQEVAGGVFPADEH
3D structure
PDB1oy0 The Crystal Structure of the First Enzyme in the Pantothenate Biosynthetic Pathway, Ketopantoate Hydroxymethyltransferase, from M. tuberculosis
ChainC
Resolution2.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.1.2.11: 3-methyl-2-oxobutanoate hydroxymethyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG C D62 E133 D45 E116
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003824 catalytic activity
GO:0003864 3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0015940 pantothenate biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1oy0, PDBe:1oy0, PDBj:1oy0
PDBsum1oy0
PubMed12842039
UniProtP9WIL7|PANB_MYCTU 3-methyl-2-oxobutanoate hydroxymethyltransferase (Gene Name=panB)

[Back to BioLiP]