Structure of PDB 1osb Chain C

Receptor sequence

>1osbC (length=282) Species: 562 (Escherichia coli) [Search protein sequence]

MLSHMVLTRQDIGRAASYYEGDASEWQGKGAEELGLSGEVDSKRFRELLA
GNIGEGHRIMRSATRQDSKERIGLDLTFSAPKSVSLQALVAGDAEIIKAH
DRAVARTLEQAEARAQARQKIQGKTRIETTGNLVIGKFRHETSRERDPQL
HTHAVILNMTKRSDGQWRALKNDEIVKATRYLGAVYNAELAHELQKLGYQ
LRYGKDGNFDLAHIDRQQIEGFSKRTEQIAEWYAARGLDPNSVSLEQKQA
AKVLSRAKKTSVDREALRAEWQATAKELGIDF

3D structure

PDB

1osb Recognition and processing of the origin of transfer DNA by conjugative relaxase TrwC.

Chain

Resolution

2.65 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	C	M1 S3 H4 S72 A73 R75 Q76 K79 R81 S89 A90 P91 K92 R128 Q129 K130 Q132 R154 Q159 H161 H163 R172 R178 A179 N182 D183 K187 N218 R226 S233 R235 T236 I239 L255 K258 K262 R266	M1 S3 H4 S62 A63 R65 Q66 K69 R71 S79 A80 P81 K82 R118 Q119 K120 Q122 R144 Q149 H151 H153 R162 R168 A169 N172 D173 K177 N208 R216 S223 R225 T226 I229 L245 K248 K252 R256	PDBbind-CN: Kd=70nM

External links

PDB	RCSB:1osb, PDBe:1osb, PDBj:1osb
PDBsum	1osb
PubMed	14625590
UniProt	Q47673

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