Structure of PDB 1o9k Chain C

Receptor sequence
>1o9kC (length=194) Species: 9606 (Homo sapiens) [Search protein sequence]
MNTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVKDIGYIFKE
KFAKAVGQGCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLN
DNIFHMSLLACALEVVMATYSRSSGTDLSFPWILNVLNLKAFDFYKVIES
FIKAEGNLTREMIKHLERCEHRIMESLAWLSDSPLFDLIKQSKD
3D structure
PDB1o9k Crystal Structure of the Retinoblastoma Tumor Suppressor Protein Bound to E2F and the Molecular Basis of its Regulation
ChainC
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide C E464 R467 F482 K530 E533 E554 E86 R89 F104 K146 E149 E170
Gene Ontology
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

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Biological Process

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Cellular Component
External links
PDB RCSB:1o9k, PDBe:1o9k, PDBj:1o9k
PDBsum1o9k
PubMed12598654
UniProtP06400|RB_HUMAN Retinoblastoma-associated protein (Gene Name=RB1)

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