Structure of PDB 1o5o Chain C

Receptor sequence
>1o5oC (length=210) Species: 2336 (Thermotoga maritima) [Search protein sequence]
HMKNLVVVDHPLIKHKLTIMRDKNTGPKEFRELLREITLLLAYEATRHLK
CEEVEVETPITKTIGYRINDKDIVVVPILRAGLVMADGILELLPNASVGH
IGIYRDPETLQAVEYYAKLPPLNDDKEVFLLDPMLATGVSSIKAIEILKE
NGAKKITLVALIAAPEGVEAVEKKYEDVKIYVAALDERLNDHGYIIPGLG
DAGDRLFRTK
3D structure
PDB1o5o Crystal structure of Uracil phosphoribosyltransferase (TM0721) from Thermotoga maritima at 2.30 A resolution
ChainC
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) R104 T108 D200 D203
Catalytic site (residue number reindexed from 1) R105 T109 D201 D204
Enzyme Commision number 2.4.2.9: uracil phosphoribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 U5P C R104 M133 A135 T136 G137 S139 Y193 I194 G199 R105 M134 A136 T137 G138 S140 Y194 I195 G200
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004845 uracil phosphoribosyltransferase activity
GO:0005525 GTP binding
GO:0016757 glycosyltransferase activity
Biological Process
GO:0006223 uracil salvage
GO:0008655 pyrimidine-containing compound salvage
GO:0044206 UMP salvage
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1o5o, PDBe:1o5o, PDBj:1o5o
PDBsum1o5o
PubMed
UniProtQ9WZI0|UPP_THEMA Uracil phosphoribosyltransferase (Gene Name=upp)

[Back to BioLiP]