Structure of PDB 1mzn Chain C

Receptor sequence
>1mznC (length=212) Species: 9606 (Homo sapiens) [Search protein sequence]
DMPVERILEAELAVEPDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDD
QVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIF
DRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKV
YASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTP
IDTFLMEMLEAP
3D structure
PDB1mzn Molecular Recognition of Agonist Ligands by RXRs
ChainC
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide C V1280 K1284 V1298 R1302 T1449 F1450 E1453 V34 K38 V52 R56 T203 F204 E207
BS02 BM6 C I1268 A1272 N1306 L1309 I1310 F1313 R1316 L1326 A1327 C1432 F1439 I22 A26 N60 L63 I64 F67 R70 L80 A81 C186 F193
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003707 nuclear steroid receptor activity
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Cellular Component
External links
PDB RCSB:1mzn, PDBe:1mzn, PDBj:1mzn
PDBsum1mzn
PubMed11981034
UniProtP19793|RXRA_HUMAN Retinoic acid receptor RXR-alpha (Gene Name=RXRA)

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