Structure of PDB 1mhe Chain C

Receptor sequence
>1mheC (length=273) Species: 9606 (Homo sapiens) [Search protein sequence]
SHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAPW
MEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGC
ELGPDRRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDAS
EAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATL
RCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVPS
GEEQRYTCHVQHEGLPEPVTLRW
3D structure
PDB1mhe Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E.
ChainC
Resolution2.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C E152 H155 E151 H154
BS02 peptide C Y7 M45 E63 I73 F74 N77 W97 K146 Y159 W167 Y171 Y6 M44 E62 I72 F73 N76 W96 K145 Y158 W166 Y170
External links
PDB RCSB:1mhe, PDBe:1mhe, PDBj:1mhe
PDBsum1mhe
PubMed9660937
UniProtP13747|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)

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