Structure of PDB 1mfq Chain C

Receptor sequence
>1mfqC (length=108) Species: 9606 (Homo sapiens) [Search protein sequence]
KHGQFTLRDMYEQFQNIMKMGPFSQILGMIPGFNEQESMARLKKLMTIMD
SMNDQELDSTDGAKVFSKQPGRIQRVARGSGVSTRDVQELLTQYTKFAQM
VKKMGGIK
3D structure
PDB1mfq Induced structural changes of 7SL RNA during the assembly of human signal recognition particle
ChainC
Resolution3.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.5.4: signal-recognition-particle GTPase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna C T377 D380 S381 M382 N383 G401 R402 R405 G409 S410 G411 T47 D50 S51 M52 N53 G71 R72 R75 G79 S80 G81
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0008312 7S RNA binding
Biological Process
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
Cellular Component
GO:0048500 signal recognition particle

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:1mfq, PDBe:1mfq, PDBj:1mfq
PDBsum1mfq
PubMed12244299
UniProtP61011|SRP54_HUMAN Signal recognition particle subunit SRP54 (Gene Name=SRP54)

[Back to BioLiP]