Structure of PDB 1lxf Chain C

Receptor sequence
>1lxfC (length=89) Species: 9606 (Homo sapiens) [Search protein sequence]
MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQ
NPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRCMKDDS
3D structure
PDB1lxf Structure of the regulatory N-domain of human cardiac troponin C in complex with human cardiac troponin I147-163 and bepridil.
ChainC
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C A22 A23 F27 M47 L48 A22 A23 F27 M47 L48
BS02 CA C V64 D65 D67 S69 T71 E76 V64 D65 D67 S69 T71 E76
BS03 BEP C L41 L48 M60 I61 V72 F77 M80 M81 L41 L48 M60 I61 V72 F77 M80 M81 PDBbind-CN: -logKd/Ki=4.10,Kd=80uM
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:1lxf, PDBe:1lxf, PDBj:1lxf
PDBsum1lxf
PubMed12060657
UniProtP63316|TNNC1_HUMAN Troponin C, slow skeletal and cardiac muscles (Gene Name=TNNC1)

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