Structure of PDB 1lqb Chain C

Receptor sequence
>1lqbC (length=150) Species: 9606 (Homo sapiens) [Search protein sequence]
PVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIH
SYRGHLWLFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKE
RCLQVVRSLVKPENYRRLDIVRSLYEDLEDHPNVQKDLERLTQERIAHQR
3D structure
PDB1lqb Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL.
ChainC
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide C N67 R69 I75 N78 W88 F91 Y98 P99 G104 T105 G106 R107 R108 H110 S111 Y112 H115 W117 N7 R9 I15 N18 W28 F31 Y38 P39 G44 T45 G46 R47 R48 H50 S51 Y52 H55 W57
External links
PDB RCSB:1lqb, PDBe:1lqb, PDBj:1lqb
PDBsum1lqb
PubMed12050673
UniProtP40337|VHL_HUMAN von Hippel-Lindau disease tumor suppressor (Gene Name=VHL)

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