Structure of PDB 1kmm Chain C

Receptor sequence
>1kmmC (length=387) Species: 562 (Escherichia coli) [Search protein sequence]
NIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFK
RAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQEQ
RLWYIGPMFRHERPQKGRYRQFHQLGCEVFGLQGPDIDAELIMLTARWWR
ALGISEHVTLELNSIGSLEARANYRDALVAFLEQHPALGDYLDEESREHF
AGLCKLLESAGIAYTVNQRLVRGLDYYNRTVFEWVTNSLGSQGTVCAGGR
YDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFKADPVVDIYLVASG
ADTQSAAMALAERLRDELPGVKLMTNHGGGNFKKQFARADKWGARVAVVL
GESEVANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG
3D structure
PDB1kmm The first step of aminoacylation at the atomic level in histidyl-tRNA synthetase.
ChainC
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.21: histidine--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HAM C E83 T85 R113 E115 Y122 F125 Q127 E131 R259 L261 Y264 T281 G304 F305 G308 R311 E80 T82 R110 E112 Y119 F122 Q124 E128 R222 L224 Y227 T244 G267 F268 G271 R274
Gene Ontology
Molecular Function
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004821 histidine-tRNA ligase activity
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0006412 translation
GO:0006427 histidyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:1kmm, PDBe:1kmm, PDBj:1kmm
PDBsum1kmm
PubMed9207058
UniProtP60906|SYH_ECOLI Histidine--tRNA ligase (Gene Name=hisS)

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