Structure of PDB 1je0 Chain C

Receptor sequence
>1je0C (length=227) Species: 2287 (Saccharolobus solfataricus) [Search protein sequence]
PVHILAKKGEVAERVLVVGDPGRARLLSTLLQNPKLTNENRGFLVYTGKY
NGETVSIATHGIGGPSIAIVLEELAMLGANVFIRYGTTGALVPYINLGEY
IIVTGASYNQGGLFYQYLRDNACVASTPDFELTNKLVTSFSKRNLKYYVG
NVFSSDAFYAEDEEFVKKWSSRGNIAVEMECATLFTLSKVKGWKSATVLV
VSDNLAKEELEKSVMDGAKAVLDTLTS
3D structure
PDB1je0 Three-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricus.
ChainC
Resolution1.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H5 G21 R25 R43 E75 R86 T89 S204 D205 L207 L219
Catalytic site (residue number reindexed from 1) H3 G19 R23 R41 E73 R84 T87 S202 D203 L205 L210
Enzyme Commision number 2.4.2.1: purine-nucleoside phosphorylase.
2.4.2.28: S-methyl-5'-thioadenosine phosphorylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PO4 C G21 R25 R86 G88 T89 G19 R23 R84 G86 T87
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016757 glycosyltransferase activity
GO:0016763 pentosyltransferase activity
GO:0017061 S-methyl-5-thioadenosine phosphorylase activity
Biological Process
GO:0009116 nucleoside metabolic process
GO:0009164 nucleoside catabolic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1je0, PDBe:1je0, PDBj:1je0
PDBsum1je0
PubMed11489901
UniProtP50389|PNPH_SACS2 Purine nucleoside phosphorylase (Gene Name=SSO2706)

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