Structure of PDB 1i7z Chain C

Receptor sequence
>1i7zC (length=219) Species: 10090 (Mus musculus) [Search protein sequence]
DLVLTQSPASLAVSLGQRATISCRASKSVSTSGYNYMHWYQQKPGQPPKL
LIYLASNLASGVPARFSGSGSGTDFTLNIHPVEEEDAATYYCLYSREFPP
WTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAK
VQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACE
VTHQGLSSPVTKSFNRGEC
3D structure
PDB1i7z Crystal structure of a cocaine-binding antibody.
ChainC
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COC C Y30 H34 L50 S91 R92 E93 Y34 H38 L54 S95 R96 E97 MOAD: Kd=0.4uM
Gene Ontology
Molecular Function
GO:0003823 antigen binding
Biological Process
GO:0002250 adaptive immune response
GO:0006955 immune response
GO:0016064 immunoglobulin mediated immune response
GO:0050853 B cell receptor signaling pathway
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0019814 immunoglobulin complex
GO:0070062 extracellular exosome
GO:0071735 IgG immunoglobulin complex
GO:0071738 IgD immunoglobulin complex
GO:0071742 IgE immunoglobulin complex
GO:0071745 IgA immunoglobulin complex
GO:0071753 IgM immunoglobulin complex
GO:0072562 blood microparticle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1i7z, PDBe:1i7z, PDBj:1i7z
PDBsum1i7z
PubMed11469854
UniProtP01834|IGKC_HUMAN Immunoglobulin kappa constant (Gene Name=IGKC)

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