Structure of PDB 1hu8 Chain C

Receptor sequence
>1hu8C (length=186) Species: 10090 (Mus musculus) [Search protein sequence]
TYQGNYGFHLGFLQSGTAKSVMCTYSPPLNKLFCQLAKTCPVQLWVSATP
PAGSRVRAMAIYKKSQHMTEVVRRCPHHERCSDGDGLAPPQHLIRVEGNL
APEYLEDRQTFRHSVVVPYEPPEAGSEYTTIHYKYMCNSSCMGGMNRRPI
LTIITLEDSSGNLLGRDSFEVRVCACPGRDRRTEEE
3D structure
PDB1hu8 Crystal structure of the mouse p53 core DNA-binding domain at 2.7 A resolution.
ChainC
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN C C173 H176 C235 C239 C75 H78 C137 C141
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:1hu8, PDBe:1hu8, PDBj:1hu8
PDBsum1hu8
PubMed11152481
UniProtP02340|P53_MOUSE Cellular tumor antigen p53 (Gene Name=Tp53)

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