Structure of PDB 1gmo Chain C

Receptor sequence
>1gmoC (length=172) Species: 9606 (Homo sapiens) [Search protein sequence]
NTIHEFKKSAKTTLIKIDPALKIKTKKVNTADQCADRCTRNKGLPFTCKA
FVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSY
KGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGG
PWCFTSNPEVRYEVCDIPQCSE
3D structure
PDB1gmo Crystal Structures of Nk1-Heparin Complexes Reveal the Basis for Nk1 Activity and Enable Engineering of Potent Agonists of the met Receptor
ChainC
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SGN C K60 T61 K62 K63 K24 T25 K26 K27
BS02 IDS C K60 R73 K24 R37
BS03 SO4 C I129 I130 G133 S135 I93 I94 G97 S99
External links
PDB RCSB:1gmo, PDBe:1gmo, PDBj:1gmo
PDBsum1gmo
PubMed11597998
UniProtP14210|HGF_HUMAN Hepatocyte growth factor (Gene Name=HGF)

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