Structure of PDB 1fz8 Chain C

Receptor sequence
>1fz8C (length=388) Species: 414 (Methylococcus capsulatus) [Search protein sequence]
SMLGERRRGLTDPEMAAVILKALPEAPLDGNNKMGYFVTPRWKRLTEYEA
LTVYAQPNADWIAGGLDWGDWTQKFHGGRPSWGNETTELRTVDWFKHRDP
LRRWHAPYVKDKAEEWRYTDRFLQGYSADGQIRAMNPTWRDEFINRYWGA
FLFNEYGLFNAHSQGAREALSDVTRVSLAFWGFDKIDIAQMIQLERGFLA
KIVPGFDESTAVPKAEWTNGEVYKSARLAVEGLWQEVFDWNESAFSVHAV
YDALFGQFVRREFFQRLAPRFGDNLTPFFINQAQTYFQIAKQGVQDLYYN
CLGDDPEFSDYNRTVMRNWTGKWLEPTIAALRDFMGLFAKLPAGTTDKEE
ITASLYRVVDDWIEDYASRIDFKADRDQIVKAVLAGLK
3D structure
PDB1fz8 Xenon and halogenated alkanes track putative substrate binding cavities in the soluble methane monooxygenase hydroxylase.
ChainC
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.13.25: methane monooxygenase (soluble).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA C D376 D378 D375 D377
BS02 2BM C E116 N282 Q283 T286 E115 N281 Q282 T285
BS03 2BM C R122 Q125 G126 R121 Q124 G125
BS04 2BM C Y119 F123 Y118 F122
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005515 protein binding
GO:0015049 methane monooxygenase [NAD(P)H] activity
GO:0016491 oxidoreductase activity
GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
Biological Process
GO:0006730 one-carbon metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1fz8, PDBe:1fz8, PDBj:1fz8
PDBsum1fz8
PubMed11297413
UniProtP18798|MEMB_METCA Methane monooxygenase component A beta chain (Gene Name=mmoY)

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