Structure of PDB 1fyr Chain C

Receptor sequence
>1fyrC (length=98) Species: 9606 (Homo sapiens) [Search protein sequence]
MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGND
VQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE
3D structure
PDB1fyr Dimer formation through domain swapping in the crystal structure of the Grb2-SH2-Ac-pYVNV complex.
ChainC
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C R67 R86 S88 S90 S96 H107 F108 K109 L120 W121 R13 R32 S34 S36 S42 H53 F54 K55 L66 W67
External links
PDB RCSB:1fyr, PDBe:1fyr, PDBj:1fyr
PDBsum1fyr
PubMed11063574
UniProtP62993|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)

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