Structure of PDB 1fwx Chain C

Receptor sequence

>1fwxC (length=590) Species: 266 (Paracoccus denitrificans)

DGSVAPGQLDDYYGFWSSGQSGEMRILGIPSMRELMRVPVFNRCSATGWG
QTNESVRIHERTMSERTKKFLAANGKRIHDNGDLHHVHMSFTEGKYDGRF
LFMNDKANTRVARVRCDVMKCDAILEIPNAKGIHGLRPQKWPRSNYVFCN
GEDETPLVNDGTNMEDVANYVNVFTAVDADKWEVAWQVLVSGNLDNCDAD
YEGKWAFSTSYNSEKGMTLPEMTAAEMDHIVVFNIAEIEKAIAAGDYQEL
NGVKVVDGRKEASSLFTRYIPIANNPHGCNMAPDKKHLCVAGKLSPTVTV
LDVTRFDAVFYENADPRSAVVAEPELGLGPLHTAFDGRGNAYTSLFLDSQ
VVKWNIEDAIRAYAGEKVDPIKDKLDVHYQPGHLKTVMGETLDATNDWLV
CLSKFSKDRFLNVGPLKPENDQLIDISGDKMVLVHDGPTFAEPHDAIAVH
PSILSDIKSVWDRNDPMWAETRAQAEADGVDIDNWTEEVIRDGNKVRVYM
SSVAPSFSIESFTVKEGDEVTVIVTNLDEIDDLTHGFTMGNYGVAMEIGP
QMTSSVTFVAANPGVYWYYCQWFCHALHMEMRGRMLVEPK

3D structure

• PDB: 1fwx Revisiting the Catalytic CuZ Cluster of Nitrous Oxide (N2O) Reductase. Evidence of a Bridging Inorganic Sulfur
• Chain: C
• Resolution: 1.6 Å

Enzymatic activity

• Enzyme Commision number: 1.7.2.4: nitrous-oxide reductase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CA	C	Y204 E207 M215 D221 N268	Y211 E214 M222 D228 N275
BS02	CA	C	D366 M424	D373 M431
BS03	CA	C	K397 E412	K404 E419
BS04	CUA	C	H526 C561 W563 C565 H569 M572	H535 C570 W572 C574 H578 M581

Gene Ontology

Molecular Function

• GO:0004129 cytochrome-c oxidase activity
• GO:0005507 copper ion binding
• GO:0005509 calcium ion binding
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding
• GO:0050304 nitrous-oxide reductase activity

Biological Process

• GO:0019333 denitrification pathway
• GO:1902600 proton transmembrane transport

Cellular Component

• GO:0016020 membrane
• GO:0042597 periplasmic space

External links

• PDB: RCSB:1fwx, PDBe:1fwx, PDBj:1fwx
• PDBsum: 1fwx
• PubMed: 11024061
• UniProt: Q51705|NOSZ_PARDE Nitrous-oxide reductase (Gene Name=nosZ)