Structure of PDB 1fq9 Chain C

Receptor sequence
>1fq9C (length=211) Species: 9606 (Homo sapiens) [Search protein sequence]
MPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPQPTLRWLKNGKEFK
PDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVV
ERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGS
KIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIG
LSHHSAWLTVL
3D structure
PDB1fq9 Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization.
ChainC
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.1: receptor protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SGN C K160 K163 K177 K12 K15 K29
BS02 UAP C T173 K175 T25 K27
BS03 IDS C K207 R209 K59 R61
External links
PDB RCSB:1fq9, PDBe:1fq9, PDBj:1fq9
PDBsum1fq9
PubMed11030354
UniProtP11362|FGFR1_HUMAN Fibroblast growth factor receptor 1 (Gene Name=FGFR1)

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