Structure of PDB 1ffx Chain C

Receptor sequence
>1ffxC (length=423) Species: 9913 (Bos taurus) [Search protein sequence]
MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDAVF
VDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDL
VLDRIRKLADQCTGLQGFSVFHSFGGGTGSGFTSLLMERLSVDYGKKSKL
EFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNL
DIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRAHF
PLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCL
LYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYEPPTVVPGGD
LAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGE
FSEAREDMAALEKDYEEVGVDSV
3D structure
PDB1ffx The 4 A X-ray structure of a tubulin:stathmin-like domain complex.
ChainC
Resolution3.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTP C Q11 A12 E71 G143 G144 T145 I171 N206 Y224 N228 Q11 A12 E54 G126 G127 T128 I154 N189 Y207 N211
Gene Ontology
Molecular Function
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0000278 mitotic cell cycle
GO:0007017 microtubule-based process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0031514 motile cilium

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Molecular Function
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Cellular Component
External links
PDB RCSB:1ffx, PDBe:1ffx, PDBj:1ffx
PDBsum1ffx
PubMed11030624
UniProtP02550|TBA1A_PIG Tubulin alpha-1A chain (Gene Name=TUBA1A)

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