Structure of PDB 1f4v Chain C

Receptor sequence

>1f4vC (length=126) Species: 562 (Escherichia coli)

ADKELKFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALNKLQAGGY
GFVISDWNMPNMDGLELLKTIRADGAMSALPVLMVTAEAKKENIIAAAQA
GASGYVVKPFTAATLEEKLNKIFEKL

3D structure

• PDB: 1f4v Crystal structure of an activated response regulator bound to its target.
• Chain: C
• Resolution: 2.22 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	C	K92 K126	K91 K125
BS02	peptide	C	A90 K91 K92 I95 A99 G105 Y106 V108 K119 K122	A89 K90 K91 I94 A98 G104 Y105 V107 K118 K121
BS03	MG	C	D13 F14 N59	D12 F13 N58
BS04	BEF	C	D57 W58 N59 T87 K109	D56 W57 N58 T86 K108

Gene Ontology

Molecular Function

• GO:0000156 phosphorelay response regulator activity
• GO:0000287 magnesium ion binding
• GO:0005515 protein binding
• GO:0016407 acetyltransferase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0000160 phosphorelay signal transduction system
• GO:0006935 chemotaxis
• GO:0007165 signal transduction
• GO:0009454 aerotaxis
• GO:0018393 internal peptidyl-lysine acetylation
• GO:0043052 thermotaxis
• GO:0050920 regulation of chemotaxis
• GO:0071977 bacterial-type flagellum-dependent swimming motility
• GO:0097588 archaeal or bacterial-type flagellum-dependent cell motility
• GO:1902021 regulation of bacterial-type flagellum-dependent cell motility

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0009288 bacterial-type flagellum
• GO:0009433 bacterial-type flagellum basal body, C ring
• GO:0120107 bacterial-type flagellum rotor complex

External links

• PDB: RCSB:1f4v, PDBe:1f4v, PDBj:1f4v
• PDBsum: 1f4v
• PubMed: 11135671
• UniProt: P0AE67|CHEY_ECOLI Chemotaxis protein CheY (Gene Name=cheY)