Structure of PDB 1ejb Chain C

Receptor sequence
>1ejbC (length=168) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
AVKGLGKPDQVYDGSKIRVGIIHARWNRVIIDALVKGAIERMASLGVEEN
NIIIETVPGSYELPWGTKRFVDRQAKLGKPLDVVIPIGVLIKGSTMHFEY
ISDSTTHALMNLQEKVDMPVIFGLLTCMTEEQALARAGIDEAHSMHNHGE
DWGAAAVEMAVKFGKNAF
3D structure
PDB1ejb The atomic structure of pentameric lumazine synthase from Saccharomyces cerevisiae at 1.85 A resolution reveals the binding mode of a phosphonate intermediate analogue.
ChainC
Resolution1.85 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H97
Catalytic site (residue number reindexed from 1) H97
Enzyme Commision number 2.5.1.78: 6,7-dimethyl-8-ribityllumazine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 INJ C I121 F122 R136 I121 F122 R136
BS02 INJ C W26 G59 S60 Y61 E62 L90 I91 G93 S94 T95 W26 G59 S60 Y61 E62 L90 I91 G93 S94 T95
Gene Ontology
Molecular Function
GO:0000906 6,7-dimethyl-8-ribityllumazine synthase activity
GO:0016740 transferase activity
Biological Process
GO:0009231 riboflavin biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005758 mitochondrial intermembrane space
GO:0009349 riboflavin synthase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1ejb, PDBe:1ejb, PDBj:1ejb
PDBsum1ejb
PubMed10860731
UniProtP50861|RIB4_YEAST 6,7-dimethyl-8-ribityllumazine synthase (Gene Name=RIB4)

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