Structure of PDB 1e6e Chain C

Receptor sequence
>1e6eC (length=456) Species: 9913 (Bos taurus) [Search protein sequence]
QTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVAPD
HPEVKNVINTFTQTARSDRCAFYGNVEVGRDVTVQELQDAYHAVVLSYGA
EDHQALDIPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQG
NVALDVARILLTPPDHLEKTDITEAALGALRQSRVKTVWIVGRRGPLQVA
FTIKELREMIQLPGTRPMLDPADFLGLQDRIKEAARPRKRLMELLLRTAT
EKPGVEEAARRASASRAWGLRFFRSPQQVLPSPDGRRAAGIRLAVTRLEG
IGEATRAVPTGDVEDLPCGLVLSSIGYKSRPIDPSVPFDPKLGVVPNMEG
RVVDVPGLYCSGWVKRGPTGVITTTMTDSFLTGQILLQDLKAGHLPSGPR
PGSAFIKALLDSRGVWPVSFSDWEKLDAEEVSRGQASGKPREKLLDPQEM
LRLLGH
3D structure
PDB1e6e Adrenodoxin Reductase-Adrenodoxin Complex Structure Suggests Electron Transfer Path in Steroid Biosynthesis.
ChainC
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H55 D159 I376 T377
Catalytic site (residue number reindexed from 1) H51 D155 I372 T373
Enzyme Commision number 1.18.1.6: adrenodoxin-NADP(+) reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD C G15 P16 A17 E38 K39 G45 L46 G50 V51 V58 V82 Y102 G103 I336 W367 V375 I376 T379 G11 P12 A13 E34 K35 G41 L42 G46 V47 V54 V78 Y98 G99 I332 W363 V371 I372 T375
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0015039 NADPH-adrenodoxin reductase activity
GO:0016491 oxidoreductase activity
GO:0050660 flavin adenine dinucleotide binding
GO:0050661 NADP binding
Biological Process
GO:0006694 steroid biosynthetic process
GO:0008203 cholesterol metabolic process
GO:0022900 electron transport chain
GO:0070995 NADPH oxidation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1e6e, PDBe:1e6e, PDBj:1e6e
PDBsum1e6e
PubMed11053423
UniProtP08165|ADRO_BOVIN NADPH:adrenodoxin oxidoreductase, mitochondrial (Gene Name=FDXR)

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