Structure of PDB 1dd1 Chain C

Receptor sequence
>1dd1C (length=241) Species: 9606 (Homo sapiens) [Search protein sequence]
NGHLQHHPPMPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVD
GYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRC
LSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCHRQMQQQA
ATAQAAAAAQAAAVAGNAPAISLSAAAGIGVDDLRRLCILRMSFVKGWGP
DYPRQSIKETPCWIEIHLHRALQLLDEVLHTMPIADPQPLD
3D structure
PDB1dd1 Crystal structure of a transcriptionally active Smad4 fragment.
ChainC
Resolution2.62 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SO4 C R416 Q442 R445 R115 Q141 R144
BS02 SO4 C R497 R502 R186 R191
BS03 SO4 C R496 R497 R502 R185 R186 R191
BS04 SO4 C K507 P514 R515 K196 P203 R204
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:1dd1, PDBe:1dd1, PDBj:1dd1
PDBsum1dd1
PubMed10647180
UniProtQ13485|SMAD4_HUMAN Mothers against decapentaplegic homolog 4 (Gene Name=SMAD4)

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