Structure of PDB 1a3g Chain C

Receptor sequence
>1a3gC (length=295) Species: 562 (Escherichia coli) [Search protein sequence]
KADYIWFNGEMVRWEDAKVHVMSHALHYGTSVFEGIRCYDSHKGPVVFRH
REHMQRLHDSAKIYRFPVSQSIDELMEACRDVIRKNNLTSAYIRPLIFVG
DVGMGVNPPAGYSTDVIIAAFPWQGIDAMVSSWNRAAPNTIPTAAKAGGN
YLSSLLVGSEARRHGYQEGIALDVNGYISEGAGENLFEVKDGVLFTPPFT
SSALPGITRDAIIKLAKELGIEVREQVLSRESLYLADEVFMSGTAAEITP
VRSVDGIQVGEGRCGPVTKRIQQAFFGLFTGETEDKWGWLDQVNQ
3D structure
PDB1a3g Three-dimensional structure of Escherichia coli branched-chain amino acid aminotransferase at 2.5 A resolution.
ChainC
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) F36 G38 K159 A160 E193 L217
Catalytic site (residue number reindexed from 1) F33 G35 K146 A147 E180 L204
Enzyme Commision number 2.6.1.42: branched-chain-amino-acid transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP C R59 K159 Y164 E193 G196 E197 G219 I220 T221 T257 R56 K146 Y151 E180 G183 E184 G206 I207 T208 T244
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004084 branched-chain-amino-acid transaminase activity
GO:0008483 transaminase activity
GO:0042802 identical protein binding
GO:0052654 L-leucine-2-oxoglutarate transaminase activity
GO:0052655 L-valine-2-oxoglutarate transaminase activity
GO:0052656 L-isoleucine-2-oxoglutarate transaminase activity
Biological Process
GO:0006532 aspartate biosynthetic process
GO:0008652 amino acid biosynthetic process
GO:0009081 branched-chain amino acid metabolic process
GO:0009082 branched-chain amino acid biosynthetic process
GO:0009097 isoleucine biosynthetic process
GO:0009098 L-leucine biosynthetic process
GO:0009099 L-valine biosynthetic process
GO:0046394 carboxylic acid biosynthetic process
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1a3g, PDBe:1a3g, PDBj:1a3g
PDBsum1a3g
PubMed9163511
UniProtP0AB80|ILVE_ECOLI Branched-chain-amino-acid aminotransferase (Gene Name=ilvE)

[Back to BioLiP]