Structure of PDB 8ove Chain By

Receptor sequence
>8oveBy (length=180) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]
MKIKSHDQITFPEDVTVSVKDRIVTVKGKRGTLTKDLRHLQLDFRVNKKL
RTFTAVRWFGNKINNSTINTALSHVRNMITGVTKGFRFKVRFAYAHFPIS
VTVENQLVEIRNFLGEKRVRRQVVADDVKVYRTDELVLEGNDLEQVSREA
AVMHQLCLVKKKDIRKFLDGIYVQTKTNIE
3D structure
PDB8ove A single pseudouridine on rRNA regulates ribosome structure and function in the mammalian parasite Trypanosoma brucei.
ChainBy
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna By K168 D169 R171 K172 K162 D163 R165 K166
BS02 rna By K4 H6 R22 Q41 R45 T54 R57 W58 K4 H6 R22 Q41 R45 T54 R57 W58
BS03 rna By H39 S66 N69 T70 S73 H74 N77 H96 F97 G115 K117 R118 S153 R154 Q161 K172 H39 S66 N69 T70 S73 H74 N77 H96 F97 G115 K117 R118 S147 R148 Q155 K166
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8ove, PDBe:8ove, PDBj:8ove
PDBsum8ove
PubMed37985661
UniProtQ38CD0

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