Structure of PDB 8oir Chain Bv

Receptor sequence
>8oirBv (length=238) Species: 9606 (Homo sapiens) [Search protein sequence]
GSPWRLLGALCLQRPPVVSKPLTPLQEEMASLLQQIEIERSLYSDHELRA
LDENQRLAKKKADLHDEEDEQDILLAQDLEDMWEQKFLQFKLGARITEAD
EKNDRTSLNRKLDRNLVLLVREKFGDQDVWILPQAEWQPGETLRGTAERT
LATLSENNMEAKFLGNAPCGHYTFKFPQAMRTESNLGAKVFFFKALLLTG
DFSQAGNKGHHVWVTKDELGDYLKPKYLAQVRRFVSDL
3D structure
PDB8oir Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
ChainBv
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna Bv F165 Q168 V170 Q175 F215 K216 R222 K265 F124 Q127 V129 Q134 F174 K175 R181 K224
BS02 VAL Bv G166 P218 M221 G125 P177 M180
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0008150 biological_process
GO:0032543 mitochondrial translation
Cellular Component
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:0030054 cell junction
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:8oir, PDBe:8oir, PDBj:8oir
PDBsum8oir
PubMed37141370
UniProtQ9H2W6|RM46_HUMAN Large ribosomal subunit protein mL46 (Gene Name=MRPL46)

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