Structure of PDB 8oir Chain Bu

Receptor sequence
>8oirBu (length=241) Species: 9606 (Homo sapiens) [Search protein sequence]
TKKRFTPPIYQPKFKTEKEFLVIPPEKSDRSIHLACTAGIFDAYVPPEGD
ARISTERMKKTMASQVSIRRIKDYDANFKIKDFPEKAKDIFIEAHLCLNN
SDHDRLHTLVTEHCFPDMTWDIKYKTVRWSFVESLEPSHVVQVRCSSMMN
QGNVYGQITVRMHTRQTLAIYDRFGRLMYGQEDVPKDVLEYVVFEKQLTN
PYGSWRMHTKIVPPWAPPKQPILKTVMIPGPQLKPEEEYEE
3D structure
PDB8oir Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
ChainBu
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna Bu T37 K38 K39 R40 F41 P44 Y46 K49 F50 K51 S72 R74 K177 Y178 T1 K2 K3 R4 F5 P8 Y10 K13 F14 K15 S28 R30 K123 Y124
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:8oir, PDBe:8oir, PDBj:8oir
PDBsum8oir
PubMed37141370
UniProtQ9BRJ2|RM45_HUMAN Large ribosomal subunit protein mL45 (Gene Name=MRPL45)

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