Structure of PDB 8ova Chain Bk

Receptor sequence

>8ovaBk (length=123) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]

IVKIRDLKEKGKDDLLKQLSEFKKELSQLRVSQQMNVGAARLGRIRTIRK
GIARIMTVLNKNERENLRKFYSDKKLRSAKPKTLRAKLTHRRRLALKANE
KNRKTRRQLRMAHKFPRRIYAVK

3D structure

PDB

8ova A single pseudouridine on rRNA regulates ribosome structure and function in the mammalian parasite Trypanosoma brucei.

Chain

Resolution

2.47 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	Bk	R80 H93 R94 K107 R109 R113 H116 R120	R77 H90 R91 K104 R106 R110 H113 R117
BS02	rna	Bk	I7 K53 R57 M59 N63 R67 K85 K90 T92 H93 R94 R96	I4 K50 R54 M56 N60 R64 K82 K87 T89 H90 R91 R93

Gene Ontology

	Molecular Function
GO:0003729	mRNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006412	translation

	Cellular Component
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links