Structure of PDB 7o80 Chain Bj

Receptor sequence

>7o80Bj (length=86) Species: 9986 (Oryctolagus cuniculus)

TKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSA
KAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPK

3D structure

• PDB: 7o80 Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.
• Chain: Bj
• Resolution: 2.9 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	Bj	T2 K3 G4 T5 S6 S7 F8 G9 K10 R11 R12 N13 K14 T15 H16 K25 H28 Q30 K31 G35 K36 R43 K44 R45 K46 Y47 N48 W49 S50 K52 A53 R55 R56 T58 T59 Y71 E80 G81 K85	T1 K2 G3 T4 S5 S6 F7 G8 K9 R10 R11 N12 K13 T14 H15 K24 H27 Q29 K30 G34 K35 R42 K43 R44 K45 Y46 N47 W48 S49 K51 A52 R54 R55 T57 T58 Y70 E79 G80 K84
BS02	rna	Bj	R20 R21 C22 G23 N57 G60 G62 R63 M64 R65 H66 L67 K68 Y71 R72 F74 H76 R79 E80 G81 T82 P84 K85 K87	R19 R20 C21 G22 N56 G59 G61 R62 M63 R64 H65 L66 K67 Y70 R71 F73 H75 R78 E79 G80 T81 P83 K84 K86
BS03	ZN	Bj	C19 C22 C34 C37	C18 C21 C33 C36

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7o80, PDBe:7o80, PDBj:7o80
• PDBsum: 7o80
• PubMed: 34029205
• UniProt: U3KPD5|RL37_RABIT Large ribosomal subunit protein eL37 (Gene Name=RPL37)