Structure of PDB 6olz Chain Bd

Receptor sequence
>6olzBd (length=51) Species: 9606 (Homo sapiens) [Search protein sequence]
QLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFIK
L
3D structure
PDB6olz Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
ChainBd
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna Bd Q5 Y7 S9 H10 P11 R12 K13 F14 S18 R22 C24 N26 H28 G29 L30 R32 Y34 N37 C39 R40 Q41 C42 R44 Q45 K54 L55 Q1 Y3 S5 H6 P7 R8 K9 F10 S14 R18 C20 N22 H24 G25 L26 R28 Y30 N33 C35 R36 Q37 C38 R40 Q41 K50 L51
BS02 ZN Bd C21 C24 S25 C17 C20 S21
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005791 rough endoplasmic reticulum
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005925 focal adhesion
GO:0015935 small ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0070062 extracellular exosome
GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:6olz, PDBe:6olz, PDBj:6olz
PDBsum6olz
PubMed31160784
UniProtP62273|RS29_HUMAN Small ribosomal subunit protein uS14 (Gene Name=RPS29)

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