Structure of PDB 5aj0 Chain Ba

Receptor sequence

>5aj0Ba (length=97) Species: 9606 (Homo sapiens) [Search protein sequence]

TKKRRNNGRAKKGRGHVQPIRCTNCARCVPKDKAIKKFVIRNIVEAAAVR
DISEASVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREARKDRTPP

3D structure

PDB

5aj0 Structural Snapshots of Actively Translating Human Ribosomes

Chain

Resolution

3.5 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	Ba	T2 K3 K4 R5 R6 N7 N8 R10 A11 K13 G14 R15 G16 H17 Q19 R28 K32 K34 K37 K38 F39 I41 V75 S76 I79 V83 V84 N86 R87 S88 R89 R92 K93 R95 T96 P97	T1 K2 K3 R4 R5 N6 N7 R9 A10 K12 G13 R14 G15 H16 Q18 R27 K31 K33 K36 K37 F38 I40 V74 S75 I78 V82 V83 N85 R86 S87 R88 R91 K92 R94 T95 P96
BS02	rna	Ba	R42 E46	R41 E45
BS03	ZN	Ba	C23 C77	C22 C76

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003729	mRNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0045296	cadherin binding

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation
GO:0033119	negative regulation of RNA splicing

	Cellular Component
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005791	rough endoplasmic reticulum
GO:0005829	cytosol
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:0016020	membrane
GO:0022626	cytosolic ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:0045202	synapse
GO:0070062	extracellular exosome
GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:5aj0, PDBe:5aj0, PDBj:5aj0
PDBsum	5aj0
PubMed	25957688
UniProt	P62854\|RS26_HUMAN Small ribosomal subunit protein eS26 (Gene Name=RPS26)