Structure of PDB 8fiz Chain BZ

Receptor sequence
>8fizBZ (length=110) Species: 562 (Escherichia coli) [Search protein sequence]
METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKV
LESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRT
SHITVVVSDR
3D structure
PDB8fiz A trailing ribosome speeds up RNA polymerase at the expense of transcript fidelity via force and allostery.
ChainBZ
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna BZ K6 H7 R8 H9 R11 S13 Q15 K16 R18 K41 K42 K49 S53 A56 N57 H60 N61 D77 E78 K83 R84 P87 R88 A89 K90 G91 R92 A93 I96 L97 K98 K6 H7 R8 H9 R11 S13 Q15 K16 R18 K41 K42 K49 S53 A56 N57 H60 N61 D77 E78 K83 R84 P87 R88 A89 K90 G91 R92 A93 I96 L97 K98
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042255 ribosome assembly
GO:0042256 cytosolic ribosome assembly
GO:0046677 response to antibiotic
GO:1902626 assembly of large subunit precursor of preribosome
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8fiz, PDBe:8fiz, PDBj:8fiz
PDBsum8fiz
PubMed36931247
UniProtP61175|RL22_ECOLI Large ribosomal subunit protein uL22 (Gene Name=rplV)

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