Structure of PDB 8oeq Chain BX

Receptor sequence

>8oeqBX (length=96) Species: 5476 (Candida albicans)

NINSKLALTIKSGKYTLGYKSVVKSLRTGKAKLVIIAANTPVLRKSELEY
YAMLSKTPVYYFQGGNNELGTVCGKLFRVGTLSILDAGDSDILSSI

3D structure

• PDB: 8oeq Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
• Chain: BX
• Resolution: 3.3 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BX	L27 G28 Y29 K30 S31 K34 N49 P51 V52 L53 R54 K55 S56 E59 L86 F87 R88 V89 G90	L17 G18 Y19 K20 S21 K24 N39 P41 V42 L43 R44 K45 S46 E49 L76 F77 R78 V79 G80

External links

• PDB: RCSB:8oeq, PDBe:8oeq, PDBj:8oeq
• PDBsum: 8oeq
• UniProt: A0A1D8PM75|RL30_CANAL Large ribosomal subunit protein eL30 (Gene Name=RPL30)