Structure of PDB 8btk Chain BX

Receptor sequence

>8btkBX (length=118) Species: 9986 (Oryctolagus cuniculus)

KIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMK
KIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYV
RLAPDYDALDVANKIGII

3D structure

• PDB: 8btk Molecular basis of the TRAP complex function in ER protein biogenesis.
• Chain: BX
• Resolution: 3.5 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BX	P44 T45 F46 R47 R48 K50 T51 R53 L54 R56 Q57 P58 K59 Y60 T83 K89 N93 N105 K106 H107 K123 N125 T126 L127 I128 P130 K134 K135 Y137 R139	P6 T7 F8 R9 R10 K12 T13 R15 L16 R18 Q19 P20 K21 Y22 T45 K51 N55 N67 K68 H69 K85 N87 T88 L89 I90 P92 K96 K97 Y99 R101
BS02	rna	BX	T51 L52 R55 R56 P66 R67 R68 K70	T13 L14 R17 R18 P28 R29 R30 K32

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0000027 ribosomal large subunit assembly
• GO:0006412 translation

Cellular Component

• GO:0005634 nucleus
• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8btk, PDBe:8btk, PDBj:8btk
• PDBsum: 8btk
• PubMed: 37170030
• UniProt: G1SE76|RL23A_RABIT Large ribosomal subunit protein uL23 (Gene Name=RPL23A)