Structure of PDB 7o81 Chain BX

Receptor sequence

>7o81BX (length=122) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

HKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTE
SAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEK
KAYVRLAPDYDALDVANKIGII

3D structure

PDB

7o81 Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.

Chain

Resolution

3.1 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BX	K37 K38 P44 T45 R47 R48 K50 T51 L52 R53 L54 R56 Q57 P58 K59 Y60 R62 T83 K89 N93 N105 K106 H107 K123 N125 L127 I128 P130 K134 K135 Y137 R139	K3 K4 P10 T11 R13 R14 K16 T17 L18 R19 L20 R22 Q23 P24 K25 Y26 R28 T49 K55 N59 N71 K72 H73 K89 N91 L93 I94 P96 K100 K101 Y103 R105
BS02	rna	BX	L52 R56 K63 P66 R67 R68 K70 H107 Q108	L18 R22 K29 P32 R33 R34 K36 H73 Q74

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:7o81, PDBe:7o81, PDBj:7o81
PDBsum	7o81
PubMed	34029205
UniProt	G1SE76\|RL23A_RABIT Large ribosomal subunit protein uL23 (Gene Name=RPL23A)