Structure of PDB 7o80 Chain BX

Receptor sequence

>7o80BX (length=118) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

KIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMK
KIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYV
RLAPDYDALDVANKIGII

3D structure

PDB

7o80 Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.

Chain

Resolution

2.9 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	BX	P44 T45 F46 R47 R48 K50 T51 R53 R56 Q57 P58 K59 Y60 R62 T83 S85 K89 N93 N105 K106 H107 K123 N125 T126 L127 I128 P130 K134 K135 Y137 R139	P6 T7 F8 R9 R10 K12 T13 R15 R18 Q19 P20 K21 Y22 R24 T45 S47 K51 N55 N67 K68 H69 K85 N87 T88 L89 I90 P92 K96 K97 Y99 R101
BS02	rna	BX	T51 R56 P66 R67 R68 K70 H107 Q108	T13 R18 P28 R29 R30 K32 H69 Q70

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:7o80, PDBe:7o80, PDBj:7o80
PDBsum	7o80
PubMed	34029205
UniProt	G1SE76\|RL23A_RABIT Large ribosomal subunit protein uL23 (Gene Name=RPL23A)